Bioss Inc.'s Synphilin 1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen. The Synphilin 1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated was generated using SNCAIP as the antigen and it reacts with Mouse, and Rat.
Description
Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1